Monday, September 27, 2010

Why does muscular dystrophy progress slower within females than males?

Duchenne's muscular dystrophy (a common form of the disease) is an x-linked recessive trait. This system that if a boy gets a copy of this gene from his mother, he will hold the disease. If a girl gets this gene from her mother, she will be a owner, because she will also have a majority x-chromosome from her father. Here's where I start speculating. For a long complicated justification called mosiacism, a woman may attain muscular dystrophy even with one regular x. I suspect that this normal x is helping to slow the diease.
Muscular dystrophy is the residence used to describe a group of inherited disorders that wreak progressive muscle weakness. There are nine types of muscular dystrophies,
Myotubular, or centronuclear, myopathy belongs to the ethnic group of congenital myopathies which are characterised by muscle weakness.
Manifesting carrier of myotubular myopathy are very dying out. As mentioned earlier, every womanly has two copies of the X chromosome. In every cell, one copy is “switched off”. Usually this is unsystematic, but in some exceptional cases, more copies of the “good” chromosome are inactivated. In such cases a feminine may show signs of the condition, but this is likely to be just mild weakness.
VR
Certain types of MD are sex associated traits, carried on the X chromosome. A male is XY whereas a womanly is XX. If the male inherits an MD-X, hes get MD. If a female inherits it, she is heterozygous and the symptoms are mild if they show at adjectives.
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