Monday, September 27, 2010

Why does increased cortisol organize to hypertension?

I know people next to hypercortisolism have symptoms similar to those of excessive Aldosterone secretion. I would guess it's a mineralocorticoid, and promotes absorbtion of Na+ at the DCT/CT. Hope this help.
It's not a mineralocortcoid really.although it does have highly slight mineralocorticoid effect. It's main function is as a glucocortioid stimulating gluconeogenesis and have a good anti-inflammatory effect. Though it does increase blood pressure to some horizontal .so maybe excess production could end in hyperstension .though a large increase contained by cortisol would usually cause a refusal feedback response to ACTH hormone, thus inhibiting it.
Froboygold has it right. Cortisol can own effects similar to Aldosterone, even though it is a glucocorticoid and not a mineralcorticoid. Increased cortisol leads to hypernatremia (high sodium level in blood serum) influential to hypervolemia (increased blood volume) and thus hypertension.

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